WebThe present Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. Skin sensitisation refers to an allergic response following skin contact with the tested chemical, as defined by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS). WebHLB值是衡量表面活性剂在溶液中性质的一个定量指标,是表明表面 活性剂亲水能力的一个重要参数。. fHLB的测定与计算. 测定 HLB值的方法有乳化法、浊点法、水数法、 气相 …
JaCVAM試験法一覧&PDF 修正 20150528 - expydoc.com
WebH. Clay Moore and Associates Inc. is a manufacturer’s representative company that has been serving the Southeast since 1898. Our customers include electric utilities, pulp and … Webh-clat法でcd86とcd54が陰性になる陽性対照物質でもしっかり反応し、llnaと同様の結果が得られた。 発熱性試験 実験動物代替法で使用するモデル細胞(Mono-Mac-6など)に … surface pen no longer works touchscreen
白细胞介素-2协同白细胞介素-18活化自然杀伤细胞活性的作用
Web「h-clat※1」が、7月29日、世界的に認められる公的試験法である「oecdテストガイドライン※2」に収載されまし た。 皮膚感作性(皮膚アレルギー反応)は生体反応の中で … Webh-CLAT Assay The h-CLAT is an in-vitro method on human dendritic-like cells (part of the immune system) expressing surface proteins needed to trigger an immune response. Increases in these proteins are detected using fluorescent-labelled antibodies and a flow cytometer. Sensitisers increase the number of these proteins on the exposed cells … [collapsed]Skin sensitisation is the regulatory endpoint aiming at the identification of chemicals able to elicit an allergic response in susceptible individuals. Following repeated exposure to a sensitising agent, the adverse health effect of allergic contact dermatitis (ACD) may be provoked. Thus the development of … See more [collapsed]The h-CLAT measures the expression of the CD86 and CD54 membrane markers in THP-1 cells, a human monocytic … See more [collapsed] In 2008, EURL ECVAM received a joint submission from Kao Corporation and Shiseido relating to h-CLAT. The method had previously been subjected to a variety of evaluation studies. On the basis … See more [collapsed]The test method addresses only one mechanisms of the cascade of events that leads to the development of skin sensitisation. On its own the method is unlikely to replace … See more [collapsed]It was found that the information generated by h-CLAT was relevant to the assessment of the skin sensitisation … See more surface pen not pairing with surface