Cisplatin pubchem

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August undefined, 2024

WebJul 12, 2024 · Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in … WebThe chemotherapeutic cisplatin causes renal dysfunction and renal proximal tubular cell (RPTC) apoptosis. The goal of these studies was to examine the role of p53, caspase 3, 8, and 9, and mitochondria in the signaling of cisplatin-induced apoptosis. Cisplatin (50 microM) produced time-dependent apo …

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WebCisplatin (cisPt) is one of the strongest anticancer agents with proven clinical activity against a wide range of solid tumors. Its mode of action has been linked to its ability to crosslink with the canonical purine bases, primarily with guanine. Theoretical studies performed at the molecular level suggest that such nonspecific interactions can also take … WebTaken together, our results support FoxO-1 as one of the key factors promoting sensitivity towards selinexor and the synergistic interaction between cisplatin and selinexor in ovarian carcinoma cells with selected molecular backgrounds, highlighting the need for treatment regimens tailored to the molecular tumor features. Keywords: chisholm bridge glen affric

Symmetry Free Full-Text Docking of Cisplatin on Fullerene ...

WebDec 15, 2016 · DOI: 10.1016/j.bcp.2016.09.022 Abstract Salinomycin, a polyether antibiotic, acts as a highly selective potassium ionophore and has anticancer activity on various cancer cell lines. Cisplatin has been proved as chemotherapy drug for advanced human non-small cell lung cancer (NSCLC). WebJan 30, 2024 · Pharmacokinetics of cisplatin administered by the pulmonary route were established in mice using dry powders inhaler (DPI) formulations showing immediate (F1) and controlled release (CR, solid lipid microparticles) in vitro, without (F2) or with PEGylated excipients (F3, F4). WebCisplatin is one of the most emetogenic chemotherapy agents, but this is managed with prophylactic antiemetics (e.g. ondansetron, granisetron, etc.) in combination with … chisholm broadband fairview ok

Salinomycin enhances cisplatin-induced cytotoxicity in human …

TP2450000 H6Cl2N2Pt ChemSpider

Webazane;dichloroplatinum Cl2H6N2Pt - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 503 National Center for Biotechnology Information 8600 Rockville Pike, … WebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. chisholm boys basketballWebCisplatin(CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts. MedChem Express, HY-17394: DNA alkylator/crosslinker MedChem Express HY-17394: Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of ... chisholm broadband tonkawa

"WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the … " - Cisplatin pubchem

Cisplatin pubchem

Cisplatin - indikasi, dosis, interaksi dan efek samping - Alomedika

WebNational Center for Biotechnology Information. 8600 Rockville Pike, Bethesda, MD, 20894 USA. Contact. Policies. FOIA. HHS Vulnerability Disclosure. National Library of Medicine. National Institutes of Health. Department of Health and Human Services. WebJan 5, 2024 · Keywords: 5-Fluorouracil (PubChem CID: 3385); Carboplatin (PubChem CID: 38904); Cell cycle arrest; Cisplatin (PubChem CID: 441203); DT-13; DT-13 (PubChem CID: 101514160); Drug combination; Gastric cancer cell; Paclitaxel (PubChem CID: 36314); Topotecan (PubChem CID: 60700); Topotecan (TPT). Copyright © 2024 Elsevier B.V. …

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WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 …

WebA stable, microcrystalline form of cisplatin, a process for its preparation, and stable, sterile dry-mix formulations thereof which are more rapidly reconstituted with sterile water to produce... Web1152 rows · Jun 13, 2005 · Cisplatin is a platinum based chemotherapy agent used to …

WebOct 1, 2014 · DOI: 10.1016/j.ijpharm.2014.07.020 Abstract SPI-077, cisplatin stealth liposome, is the best illustration of poor cisplatin release from liposomes and the subsequent negligible therapeutic activity. For this reason, optimizing drug release kinetics is … WebC2210000 Cisplatin European Pharmacopoeia (EP) Reference Standard Synonym (s): cis-Diammineplatinum (II) dichloride, cis-Dichlorodiammine platinum (II), cis-Platinum (II) diammine dichloride, Cisplatin Linear Formula: Pt (NH3)2Cl2 CAS Number: 15663-27-1 Molecular Weight: 300.05 EC Number: 239-733-8 MDL number: MFCD00011623 …

WebJan 1, 2024 · Cisplatin atau sisplatin merupakan obat kemoterapi berbasis platinum yang digunakan untuk terapi kanker, seperti kanker ovarium, testis, dan kandung kemih. Cisplatin adalah salah satu obat antikanker yang paling banyak digunakan karena efikasinya yang luas untuk terapi berbagai jenis kanker.

WebWe present MSA as a promising chemotherapeutic agent with synergistic antiproliferative effects with cisplatin. Keywords: Akt; Cisplatin; Cisplatin (PubChem CID: 441203); FOXO; LY294002 (PubChem CID: 3973); Methylseleninic acid; Methylseleninic acid (PubChem CID: 161597); PI3K; Selenium; Sodium selenite (PubChem CID: 24934). chisholm brittain texasWebJun 15, 2024 · Keywords: 3-MethylAdenine (3-MA) (PubChem CID: 1673); 5-Fluorouracil (5-FU) (PubChem CID: 3385); Allicin (PubChem CID: 65036); Apatinib (PubChem CID: 45139106); Arsenic trioxide (As (2)O (3)) (PubChem CID: 14888); Autophagy; Bafilomycin A1 (PubChem CID: 6436223); Bortezomib (PubChem CID: 387447); Brefeldin A … chisholm broadband reviewsWebChemical Name. cis-Diaminodichloroplatinum. Biological Activity. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis. chisholm broadband enidWebDimethylsulfoxid hat entzündungshemmende ( antiphlogistische) und schmerzlindernde ( analgetische) Eigenschaften. [8] [20] Es findet daher therapeutische Verwendung als perkutanes (lat. durch die Haut) Arzneimittel zur Behandlung lokaler Schmerzzustände (beispielsweise bei Sportverletzungen oder rheumatischen Beschwerden). chisholm b\u0026b stratfordWebCisplatin (10 mg) is clear to light yellow in color. Do not use Cisplatin (10 mg) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged. Drinking extra fluids while you are taking Cisplatin (10 mg) is recommended, especially before and for 24 hours after you receive Cisplatin (10 mg). chisholm brothersWebFeb 17, 2016 · Keywords: Atropine (PubChem CID: 174174); Carbachol (PubChem CID: 5831); Cisplatin (PubChem CID: 2767); Esophageal smooth muscle cells; GR113808 (PubChem CID: 119376); Gastric emptying; Gastro-intestinal system; Gastrointestinal transit; L-NNA (PubChem CID: 440005); Lonicerae Japonicae Thunberg; Loperamide … chisholm building call centerCisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein. Common side effects include bone marrow suppression, hearing problems, incl… chisholm building