CISH probes are approximately 20 nucleotides in length and are designed for DNA targets. They are complementary to the targeted sequence and bind to it after a denaturation and hybridization step. Only a few CISH probes are available commercially, so for most applications they have to be extracted, … See more Chromogenic in situ hybridization (CISH) is a cytogenetic technique that combines the chromogenic signal detection method of immunohistochemistry (IHC) techniques with in situ hybridization. It was developed around the year … See more Compared to FISH FISH is considered to be the gold standard for the detection of chromosomal abnormalities because it is very sensitive and has high … See more Silver-enhanced in situ hybridization (SISH) SISH uses a similar method as CISH, but a silver precipitate is the end product rather than a brown product. In this method, a probe tagged with dinitrophenol (DNP) binds … See more Probe design Probe design for CISH is very similar to that for FISH with differences only in labelling and detection. FISH probes are generally labelled with a variety of different fluorescent tags and can only be detected under a … See more CISH is frequently applied to assess gene amplification, such as HER-2/neu status in breast cancer samples. HER-2/neu amplification is associated with higher mortality, higher … See more WebThe CISH technique uses digoxigenin-labeled DNA probes that are specific for the HER2 gene locus on chromosome 17q11.2-21 to hybridize to the complementary nucleic acids present in the breast cancer specimen. The labeled HER2 probe is made using Subtraction Probe Technology (SPT™), a proprietary and patented technology
A modified automated protocol for EBER in situ …
WebA comprehensive range of probes, detection, ancillaries, and instruments for automated or manual ISH detection in fluorescence and brightfield applications. WebEach Zyto Fast and Zyto Fast PLUS CISH Implementation Kit includes a detailed protocol, all necessary reagents as well as positive and negative control probes for versatile use in DNA as well as RNA in situ … small wooden baseball bats for sale
EBER RNA CISH Probe Agilent
Webcish probe ( Roche ) Roche is a verified supplier Roche manufactures this product About News Press Release Team Advisors Partners Contact Bioz Stars Bioz vStars 86 Buy from Supplier Structured Review Roche Cish Probe, supplied by Roche, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. WebThe probe is intended to be used in combination with the CISH Implementation HRP-DAB Kit, which provides necessary reagents for specimen pretreatment and post-hybridization … WebJul 21, 2014 · The probes comprised 2 haptenated riboprobes each approximately 500 base pairs long directed against the conserved regions of either KAPPA or LAMBDA mRNA. The dual colors consisted of silver deposition (black) for KAPPA light chain and a novel (pink) chromogen for LAMBDA light chain. small wooden beads craft